This will be of particular interest to the descendants of Reyes-Medina lines.
I was able to locate the marriage of Antonio de los Reyes to Isabel de Esparza, although she is listed as Isabel de Hortiz, daughter of Juan de Ortiz and Luisa de Esparza. I then found the marriage of Isabel's parents:

Juan de Ortiz married Luisa de Esparza on Dec. 13, 1666 in Aguascalientes (no parents listed, thus maybe someone has more info on this couple).

Their daughter, Isavel de Esparza, was born about 1667 and died before 1709.
Isavel (Isabel) appeared as Isabel Hortiz (Ortiz) in her marriage to Antonio de los Reyes, as Isabel de Esparza in the christening of her son Luis de Reyes and in the wedding of her son Joseph de Reyes, and as Isabel Ramirez in Luis' burial. I've not figured out the source of Ramirez.

Isabel de Esparza married Antonio de Los Reyes on Nov. 11, 1681 in Aguascalientes, Aguascalientes. Antonio, son of Luis de Los Reyes (Luis1) and Juana Tiscareño de Molina, was born about 1665 and died on an unknown date.

Children of Isabel de Esparza and Antonio de Los Reyes were:

Joseph de Reyes , born about 1685 and died on an unknown date. Joseph married Beatris de Medina on Mar. 11, 1709 in El Sagrario, Aguascalientes. Beatris, was daughter of Christobal de Medina and Maria de Avila, and was born on Apr. 16, 1687 in Aguascalientes; died on an unknown date.

and

Luis de Reyes, born on Apr. 27, 1693 in Aguascalientes, and died on Apr. 14, 1742 in Aguascalientes.Luis married Gabriela de Medina, also daughter of Christobal de Medina and Maria de Avila, on Nov. 14, 1714 in El Sagrario, Aguascalientes.